Disseminated Histoplasmosis in an Indonesian HIV-Positive Patient: A Case Diagnosed by Fine Needle Aspiration Cytology

Authors

  • Nungki Anggorowati Department of Anatomical Pathology, Universitas Gadjah Mada - Sardjito Hospital, Yogyakarta Special Province, Indonesia
  • Rita C Sulistyaningsih Department of Anatomical Pathology, Universitas Gadjah Mada - Sardjito Hospital, Yogyakarta Special Province, Indonesia
  • Ahmad Ghozali Department of Anatomical Pathology, Universitas Gadjah Mada - Sardjito Hospital, Yogyakarta Special Province, Indonesia
  • Yanri W Subronto Department of Internal Medicine, Universitas Gadjah Mada - Sardjito Hospital, Yogyakarta Special Province, Indonesia

Keywords:

histoplasmosis, HIV, fine needle aspiration

Abstract

A 30-year-old Javanese-Indonesian man was admitted with complaints of 3 months persistent fever, weight loss, and fatigue. He had never known his past history of unprotected HIV until the admission. His only risk factor is unsafe sex. The patient seemed well nourished. Physical examination revealed blood pressure 100/60 mmHg, pulse 100 beats per minute, respiratory rate 20 times per minute, and temperature 38.8°C. Multiple cervical and inguinal lymphadenopathies were also found. Electrocardiogram showed anterolateral ischemic finding, whereas chest X-ray were normal. Laboratory test results revealed pancytopenia with hemoglobin of 8.2 g/dL, leucocyte count 2000 cells/mm3, platelet 78000 cells/mm3, hematocrit 25.8%, AST 162 IU/L, ALT 81 IU/L, decreased albumin of 2.72 g/dL. The clinical differential diagnosis were lymphoma or tuberculosis lymphadenopathy.

References

Satyanarayana S, Kalghatgi AT. Utility of fine needle aspiration cytology in the diagnosis of infective lesions. Diagn Histopathol. 2011;17:301-12.

Doughan A. Disseminated histoplasmosis: case report and brief review. Travel Med Infect Dis. 2006;4:332-5.

Kauffman CA. Histoplasmosis: a clinical and laboratory update. Clin Microbiol Rev. 2007;20:115-32.

Subbalaxmi MV, Umabala P, Paul R, Chandra N, Raju YS, Rudramurthy SM. A rare presentation of progressive disseminated histoplasmosis in an immunocompetent patient from a non-endemic region. Med Mycol Case Rep. 2013;2:103-7.

Jeong HW, Sohn JW, Kim MJ, et al. Disseminated histoplasmosis and tuberculosis in a patient with HIV infection. Yonsei Med J. 2007;48:531-4.

Ebenye CM. A case of disseminated histoplasmosis detected in peripheral blood smear staining revealing AIDS at terminal phase in a female patient from cameroon. Case Rep Med. 2012;2012:215207.

Aide MA. Chapter 4--histoplasmosis. J Bras Pneumol. 2009;35:1145-51.

Downloads

Published

2018-01-19

How to Cite

Anggorowati, N., Sulistyaningsih, R. C., Ghozali, A., & Subronto, Y. W. (2018). Disseminated Histoplasmosis in an Indonesian HIV-Positive Patient: A Case Diagnosed by Fine Needle Aspiration Cytology. Acta Medica Indonesiana, 49(4), 360. Retrieved from http://actamedindones.org/index.php/ijim/article/view/701

Issue

Vol. 49 No. 4 (2017): Acta Medica Indonesiana

Section

MEDICAL ILLUSTRATION

License

Copyright

The authors who publish in this journal agree to the following requirements:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a  Creative Commons Attribution 4.0 International License (CC BY 4.0) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) before and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work. (See The Effect of Open Access)

Privacy Statement

The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.