Comparison of Quality of Life between Patients Undergoing Chronic Hemodialysis with Reusable Dialyzer and Single-Use Dialyzer: A Retrospective Cohort Study

Lucky Aziza Bawazier, Suhardjono Suhardjono

Abstract


Background: in Indonesia, majority of hemodialysis centers use reusable dialyzer for cost efficiency reason. Currently, there is no available data regarding the quality of life of the end stage-renal disease patient’who use reusable dialyzer measured by a standardized questionnaire, as it was stated that at molecular level, reusable dialyzer could worsen leukocyte activity and could affect patients’ complaints and symptoms.
Methods: this was a retrospective cohort study which involved 39 subjects. All subjects underwent hemodialysis at Cipto Mangunkusumo Hospital. The study was conducted in March – September 2017. All subjects had experienced two kinds of dialyzers, the reusable dialyzers (before 2015) and the single-use dialyzers (after 2015). Of all patients, 19 patients did not know the change of dialyzers. Subjects were interviewed with Kidney Disease Quality of Life-Short Form 36 questionnaire. Results: in kidney disease component dimension, there was a significant mean difference between reusable group (68.74; SD 13.22) and single-use group (74.87; SD 13.54) (Wilcoxon test, p=0.01). The Physical Component Summary dimension, in reusable group was 63.65; SD 27.07 and in single-use group was 69.38; SD 23.07 (Wilcoxon test, p=0.217). The Mental Component Summary dimension, in reusable group was 71.78; SD 21.54 and in single-use group was75.27; SD 22.30 (Wilcoxon test, p=0.127). Bivariate analysis and further analysis showed significant association between income less than 5 million rupiah and low quality of life (p=0.048). Conclusion: the reusable dialyzer membrane lowers the ESRD patients’ quality of life influenced by another factor such as low income.

Keywords


Kidney disease quality of life; end-stage renal disease patients; reusable dialyzer; single-use dialyzer

References


Kementerian Kesehatan Republik Indonesia. Riset kesehatan dasar. Jakarta: Kemenkes RI; 2013. p. 132.

Perkumpulan Nefrologi Indonesia. 7th report of Indonesian renal registry. Jakarta: PERNEFRI; 2014.

Galvao TF, Silva MT, Araujo ME, Bulbol WS, Cardoso AL. Dialyzer reuse and mortality risk in patients with end-stage renal disease: a systematic review. Am J Nephrol. 2012;35:249-8.

Upadhyay A, Sosa MA, Jaber BL. Single-use versus reusable dialyzers: the known unknowns. Clin J Am Soc Nephrol. 2007;2:1079-86.

Jaar BG, Chang A, Plantinga L. Can we improve quality of life of patients on dialysis? Clin J Am Soc Nephrol. 2013;8:1-4.

Theofilou P. Quality of life in patients undergoing hemodialysis or peritoneal dialysis treatment. J Clin Med Res. 2011;3(3):132-8.

Maldiyono B, Moeslichan S, Sastroasmoro S, Budiman I, Purwanto SH. Perkiraan besar sampel. In: Sastroasmoro S, Ismael S, eds. Dasar-dasar metodologi penelitian klinis. 4th edition. Jakarta: CV Sagung Seto; 2011. p. 360.

Rivara MB, Cohen CR, Kestenbaum B, et al. Changes in symptom burden and physical performance with initiation of dialysis in patients with chronic kidney disease. Hemodial Int. 2015;19(1):147-50.

Finkelstein FO. Performance measures in dialysis facilities: what is the goal? CJASN. 2015;10(1):156-8.

Al-Jumaih A, Al-Onazi K, Binsalih S, Hejaili F, Al-Sayyari A. A study of quality of life and its determinants among hemodialysis patients using the KDQOL-SF instrument in one center in Saudi Arabia. Arab J Nephrol Transplant. 2011;4(3):125-30.

Sathvik BS, Parhthasarathi G, Narahari MG, Gurudev KC. An assessment of the quality of life in hemodialysis patients using the WHOQOL-BREF questionnaire. Indian J Nephrol. 2008;18(4):141-9.

Watanabe Y, Ohno Y, Inoue T, Takane H, Okada H, Suzuki H. Home hemodialysis and conventional in-center hemodialysis in Japan: a comparison of health-related quality of life. Hemodial Int. 2014;18:532-8.

Lemos CF, Rodrigues MP, Veiga JRP. Family income is associated with quality of life in patients with chronic kidney disease in the pre-dialysis phase: a cross sectional study. Health Qual Life Outcomes. 2015;13:202.

Manavalan M, Majumdar A, Kumar KTH, Priyamvada PS. Assessment of health-related quality of life and its determinants in patients with chronic kidney disease. Indian J Nephrol. 2017;27(1):37-43.

Fukushima RLD, Menezes ALC, Inouye K, Pavarini SCI, Orlandi FDS. Quality of life and associated factors in patients with chronic kidney disease on hemodialysis. Acta Paul Enferm. 2016;29(5):518-24.

Manen JGV, Korevaar JC, Dekker FW, Reuselaars MC, Boeschoten EW, Krediet RT, et al. Changes in employment status in end-stage renal disease patients during tjeir first year of dialysis. Peritoneal Dialysis International. 2001;21:595-601.

Rao M, Guo D, Jaber BL, et al. Dialyzer membrane type and reuse practice influence polymorphonuclear leukocyte function in hemodialysis patients. Kidney International. 2004;65:682-91.

National Kidney Foundation. A clinical update on dialyzer membranes: state-of-the-art considerations for optimal care in hemodialysis. NKF: New York; 2017.

Pereira BJG, Natov SN, Sundaram S, et al. Impact of single use versus reuse of cellulose dialyzers on clinical parameters and indices of biocompatibility. J Am Soc Nephrol. 1996;7:861-70.

Feldman HI, Bilker WB, Hackett MH, et al. Association of dialyzer reuse with hospitalization and survival rates among U.S. hemodialysis patients: do comorbidities matter? J Clin Epidemiol. 1999;209-17.

Poppe C, Crombez G, Hanoulle I, Vogelaers D, Petrovic M. Improving quality of life in patients with chronic kidney disease: influence of acceptance and personality. Nephrol Dial Transplant. 2013;28(1):116-21.

Cruz MC, Andrade C, Urrutia M, Draibe S, Martins LAN, Sesso RDCC. Quality of life in patients with chronic kidney disease. Clinics. 2011;66(6):991-5.


Full Text: PDF

Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 Acta Medica Indonesiana