Factors Related to Knowledge, Perception, and Practices Towards COVID-19 Among Patients with Autoimmune Diseases: A Multicenter Online Survey
Background: autoimmune patients can be more susceptible to infection. Proper knowledge, perception, and practices towards COVID-19 are essential for these patients during pandemic. This study aimed to know their knowledge, perception, and practices regarding COVID-19. Methods: cross sectional study using online survey was conducted from April to May 2020. Patients with autoimmune disease were asked about demographic characteristics, diagnosis, history of treatment, knowledge, perception, and practice regarding COVID-19. Results: there were 685 respondents. Most of them were female and had systemic lupus erythematosus with median age of 37 years old. Almost all respondents had good knowledge regarding transmission of COVID-19 and did proper prevention practices. Adequacy of information and steroid or mycophenolate mofetil/mycophenolic acid (MMF/MPA) use were related to perception of the effect of pandemic to their own health. Visiting private clinic and receiving hydroxychloroquine/chloroquine sulfate or sulfasalazine were related to perception that autoimmune conditions would make them more prone to COVID-19. Work from home was related to perception that when contracting COVID-19, the symptoms would be more severe. Living in Sumatra region and getting hydroxychloroquine/chloroquine sulfate or MMF/MPA were related to perception that autoimmune medications could reduce risk of getting COVID-19. Adequate information, university education, private clinic visit, and hydroxychloroquine/chloroquine sulfate use were related to perception that COVID-19 pandemic would cause difficulties in getting medications. Conclusion: almost all respondents had good knowledge and practices regarding COVID-19. Adequacy of information, autoimmune treatment, work from home, educational background, area of living, and health care facilities contributed to perception regarding COVID-19 pandemic.
WHO Director-General’s opening remarks at the media briefing on COVID-19 - 11 March 2020 [Internet]. who.int. 2020 [cited 30 June 2020]. Available from: https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020
Novel Coronavirus [Internet]. Who.int. 2020 [cited 30 June 2020]. Available from: https://www.who.int/indonesia/news/novel-coronavirus
Maggi E, Canonica GW, Moretta L. COVID-19: Unanswered questions on immune response and pathogenesis. J Allergy Clin Immunol. 2020;146(1):18–22. doi: 10.1016/j.jaci.2020.05.001.
Bellone M. Autoimmune Disease: Pathogenesis. eLS. 2015:1-9. doi: 10.1002/9780470015902.a0001276.pub4.
Hahn BH, King JK. Treatment of autoimmune disease: established therapies. In: Rose N, Mackay I, eds. The autoimmune diseases. 5th ed. San Diego, London, Waltham: Elsevier; 2014. p. 1209-17.
Bedford J, Enria D, Giesecke J, et al. COVID-19: towards controlling of a pandemic. Lancet. 2020;395:1015–8. doi: 10.1016/ S0140-6736(20)30673-5.
Desai MK, Brinton RD. Autoimmune Disease in Women: Endocrine Transition and Risk Across the Lifespan. Front Endocrinol (Lausanne). 2019;10:265.doi: 10.3389/fendo.2019.00265.
Amador-Patarroyo MJ, Rodriguez-Rodriguez A, Montoya-Ortiz G. How does age at onset influence the outcome of autoimmune diseases? Autoimmune Dis. 2012;2012:ID 251730. doi:10.1155/2012/251730.
Pratama MK, Atik N, Hamijoyo L. The pattern of joints involvement in patients with rheumatoid arthritis in Rheumatology Clinic Dr. Hasan Sadikin General Hospital Bandung. Indones J Rheumatol. 2017;9(2):4-7.
Wiseman V, Thabrany H, Asante A, et al. An evaluation of health systems equity in Indonesia: study protocol. Int J Equity Health. 2018;17:138. doi: 10.1186/s12939-018-0822-0.
Manhendrata Y, Trisnantoro L, Listyadewi S, et al. The Republic of Indonesia Health System Review, Health Systems in Transition. 2017;7(1):1-291.WHO Regional Office for South-East Asia. Available from: https://apps.who.int/iris/handle/10665/254716.
Chandrashekara S. The treatment strategies of autoimmune disease may need a different approach from conventional protocol: a review. Indian J Pharmacol. 2012;44(6):665-71. doi: 10.4103/0253-7613.103235.
Abd-Alrazaq A, Alhuwail D, Househ M, et al. Top Concerns of Tweeters During the COVID-19 Pandemic: Infoveillance Study. J Med Internet Res. 2020;22(4):e19016. doi: 10.2196/19016.
Ko NY, Lu WH, Chen YL, et al. COVID-19-related information sources and psychological well-being: An online survey study in Taiwan. Brain Behav Immun.2020;87:153-4. doi: 10.1016/j.bbi.2020.05.019.
Basch CE, Basch CH, Hillyer GC, et al. The Role of YouTube and the Entertainment Industry in Saving Lives by Educating and Mobilizing the Public to Adopt Behaviors for Community Mitigation of COVID-19: Successive Sampling Design Study. JMIR Public Health Surveill. 2020;6(2):e19145. doi:10.2196/19145.
Muller J. Number of internet users in Indonesia [Internet]. 2019 [Accessed 2020 June]. 12]. Available from: https://www.statista.com/statistics/254456/number-of-internet-users-in-indonesia/.
Saqlain M, Munir MM, Rehman SU, et al. Knowledge, attitude, practice and perceived barriers among healthcare workers regarding COVID-19: a cross-sectional survey from Pakistan. J Hospital Infect. 2020;105:419-23. doi: 10.1016/j.jhin.2020.05.007.
Azlan AA, Hamzah MR, Sern TJ, et al. Public knowledge, attitudes and practices towards COVID-19: A cross-sectional study in Malaysia. PLoS ONE. 2020;15(5):e0233668. doi: 10.1371/journal.pone.0233668.
Perez-Fuentes MC, Jurado MMM, Ruiz NFO, et al. Questionnaire on Perception of Threat from COVID-19. J Clin Med. 2020;9:1196. doi:10.3390/jcm9041196.
World Health Organization. Guidance on routine immunization services during COVID-19 pandemic in the WHO European Region. 2020.
Huang Y, Zhao N. Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey. Psychiatry Res. 2020;288:112954. doi: 10.1016/j.psychres.2020.112954.
Oh C-M, Kim HY, Na HK, et al. The Effect of Anxiety and Depression on Sleep Quality of Individuals With High Risk for Insomnia: A Population-Based Study. Front Neurol. 2019;10:849. doi: 10.3389/fneur.2019.00849.
Morgan C, McBeth J, Cordingley L, et al. The influence of behavioural and psychological factors on medication adherence over time in rheumatoid arthritis patients: a study in the biologics era. Rheumatology. 2015;54(10):1780-91. doi: 10.1093/rheumatology/kev105.
Yazdany J, Kim AHJ. Use of hydroxychloroquine and chloroquine during the COVID-19 pandemic: what every clinician should know. Ann Int Med. 2020;172(11):754-5. doi: 10.7326/M20-1334.
Recovery Trial. No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19. Available from: https://www.recoverytrial.net/news/statement-from-the-chief-investigators-of-the-randomised-evaluation-of-covid-19-therapy-recovery-trial-on-hydroxychloroquine-5-june-2020-no-clinical-benefit-from-use-of-hydroxychloroquine-in-hospitalised-patients-with-covid-19
Konig MF, Kim AH, Scheetz MH, et al. Baseline use of hydroxychloroquine in systemic lupus erythematosus does not preclude SARS-CoV-2 infection and severe COVID-19. Ann Rheum Dis. 2020;79(10):1386–8. doi:10.1136/annrheumdis-2020-217690.
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