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  2. Vol 52, No 4 (2020)
  3. Rajabto

Priapismus as Leukostasis Manifestation in Chronic Myeloid Leukemia

Wulyo Rajabto, Jane A.C. Djianzonie, Livy B Pratisthita, Hamzah Shatri

Abstract


Chronic Myeloid Leukemia (CML) is a myeloproliferative disease characterized by the presence of Philadelphia chromosome or BCR-ABL oncogene fusion. Patients with CML commonly present in the chronic phase with chief complaint of abdominal pain or early satiety. Priapism as the first manifestation of CML is a rare phenomenon. Priapism as a consequence of leukostasis is a urological emergency that requires immediate intracavernosus therapy followed by systemic therapy. We report a 44-year-old male patient presenting with priapism as the first manifestation of CML.


Keywords


priapismus; leukostasis; chronic myeloid leukemia

References


Jameel T, Mehmood K. Priapism – An unusual presentation in chronic myeloid leukaemia: case report and review of the literature. Biomedica. 2009;25:197–9.

Rodgers R, Latif Z, Copland M. How I manage priapism in chronic myeloid leukaemia patients. Br J Haematol. 2012;158(2):155–64.

Montague D, Jarow J, Broderick, et al. The management of erectile dysfunction: an AUA update. J Urol. 2010;174:230–9.

Gupta A, Seth T, Gupta A. Successful use of terbutaline in persistent priapism in a 12-year-old boy with chronic myeloid leukemia. Pediatr Hematol Oncol. 2009;26(1):70–3.

Hochhaus A, Kantarjian H. The development of dasatinib as a treatment for chronic myeloid leukemia (CML): from initial studies to application in newly diagnosed patients. J Cancer Res Clin Oncol. 2013;139:1971–84.


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