The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes

Authors

  • Catarina Budyono Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Siti Setiati Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital. Jakarta, Indonesia
  • Dyah Purnamasari Division of Endocrinology and Metaboism, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital. Jakarta, Indonesia
  • Cleopas M Rumende Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Keywords:

diabetes mellitus, elderly, HbA1c, orthostatic hypotension

Abstract

Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who sought treatment at outpatient clinic of Geriatry and Diabetes Division at Cipto Mangunkusumo Hospital between January and March 2016. Orthostatic hypotension was defined as a decrease in systolic blood pressure ≥20 mmHg and/or diastolic pressure ≥10 mmHg within 3 minutes after changing position from lying to standing. HbA1c levels was measured using Nycocard from Axis Shield. Chi square test was used for bivariate analysis and logistic regression was used for multivariate analysis against confounding variables. Results: the proportion of orthostatic hypotension in elderly subjects with DM was 27.4%. Median of HbA1c levels was higher in subjects with than without orthostatic hypotension (7.6% vs. 7.1%; p<0.05). There was an association between HbA1c levels of ≥7.35% and the incidence of orthostatic hypotension (OR 1.987, 95% CI 1.2-3.2). The duration of having DM was a confounding variable. Conclusion: orthostatic hypotension is more common in elderly subjects with DM. There is an association between the incidence of orthostatic hypotension and increased HbA1c levels in elderly patients with diabetes mellitus.

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Published

2016-09-21

How to Cite

Budyono, C., Setiati, S., Purnamasari, D., & Rumende, C. M. (2016). The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes. Acta Medica Indonesiana, 48(2), 122-128. Retrieved from https://actamedindones.org/index.php/ijim/article/view/150

Issue

Vol. 48 No. 2 (2016): Acta Medica Indonesiana

Section

ORIGINAL ARTICLE

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