The Correlation Between HbA1c and Neuropathy Disability Score in Type 2 Diabetes

Authors

  • Ilsa Hunaifi Department of Neurology, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia http://orcid.org/0000-0002-9745-0053
  • I Gusti Ngurah Ommy Agustriadi Department of Internal Medicine, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia.
  • I Gede Yasa Asmara Department of Internal Medicine, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia.
  • Catharina Budyono Department of Internal Medicine, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia.

Keywords:

HbA1c, neuropathy, endocrinology, diabetes mellitus

Abstract

Background: World Health Organization (WHO) estimates the incidence of type 2 diabetes in Indonesia would increase to 21.3 million in 2030. Diabetes has a chronic complications, including peripheral neuropathy. The degree of neuropathy was assessed through the Neuropathy Disability Score (NDS). In contrast, haemoglobin A1c is glycated haemoglobin used to monitor the glucose levels of diabetic patients in the last 2 or 3 months. The relationship between HbA1c and diabetic neuropathy carried out by electrodiagnosis showed that HbA1c and age were the main predictors of diabetic neuropathy. However, electrodiagnosis is still considered costly. Research is needed to determine the relationship between HbA1c and NDS to reduce morbidity. This study aims to determine the relationship between the severity of diabetic neuropathy as measured by NDS with HbA1c level in type 2 Diabetes. Methods: this cross-sectional study involved correlation analysis.. The collected data were analyzed with the Spearman correlation test. Results: approximately 56 diabetic patients were involved in this study. Patients were recruited from the internal medicine outpatient ward from the West Nusa Tenggara General Hospital. The mean age was 59.55 (SD 9.48) with 57.1% female; the median duration of diabetes was 5.5 years. The median NDS score is 7.5 and the median HbA1c value is 8.65. Spearman correlation analysis shows a correlation coefficient of 0.487 with a value of p = 0.000. Conclusion: there is a relationship between HbA1c level and the severity of diabetic neuropathy in Type 2 DM.

Author Biographies

Ilsa Hunaifi, Department of Neurology, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia

Department of Neurology University of Mataram

I Gusti Ngurah Ommy Agustriadi, Department of Internal Medicine, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia.

Department of Internal Medicine University of Mataram-West Nusa Tenggara General Hospital

I Gede Yasa Asmara, Department of Internal Medicine, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia.

Department of Internal Medicine University of Mataram-West Nusa Tenggara General Hospital

Catharina Budyono, Department of Internal Medicine, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, NTB, Indonesia.

Department of Internal Medicine University of Mataram-West Nusa Tenggara General Hospital

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Published

2021-07-11

How to Cite

Hunaifi, I., Agustriadi, I. G. N. O., Asmara, I. G. Y., & Budyono, C. (2021). The Correlation Between HbA1c and Neuropathy Disability Score in Type 2 Diabetes. Acta Medica Indonesiana, 53(2), 164. Retrieved from https://actamedindones.org/index.php/ijim/article/view/1572

Issue

Vol. 53 No. 2 (2021): Acta Medica Indonesiana

Section

ORIGINAL ARTICLE

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