Unusual Presentation of Unilateral Choroidal Melanoma with Bilateral Vasculitis in Young Individual: A Case Report and Review of Literature

Saleh S Algamdi, Dhoha M Alhamad

Abstract


Ocular melanoma stands as the predominant primary intraocular malignancy, albeit infrequently exhibiting ipsilateral inflammatory manifestations. In this article, we present an exceptional case involving a middle-aged male who presented with unilateral ocular choroidal melanoma alongside bilateral retinal vasculitis. The patient initially received temporary steroid treatment, followed by brachytherapy, which contributed to the resolution of vasculitis symptoms. The study aims to document the atypical occurrence of bilateral retinal vasculitis, which could potentially masquerade as melanoma, emphasizing the need for heightened vigilance and further investigations when encountering choroidal masses in its presence. Future research endeavors are warranted to better understand the incidence of such occurrences in this context.


Keywords


Melanoma; Vasculitis; Uveal Melanoma; Choroidal Melanoma; Macular Lesion; Uveitis; Ocular melanoma; masquerade.

References


Seregard S. Posterior uveal melanoma: the Swedish perspective. Acta Ophthalmol Scand. 1996;74:315-29.

Kivela T. The epidemiologic challenge of the most frequent eye cancer: retinoblastoma, an issue of birth and death. Br J Ophthalmol 2009;93:1129–31.

Fraser DJ, Font RL. Ocular inflammation and hemorrhage as initial manifestations of uveal malignant melanoma: Incidence and prognosis. Arch Ophthalmol. 1979;97(7):1311–4.

Steel DH, Mahomed I, Sheffield E. Unilateral choroidal melanoma with bilateral retinal vasculitis. Br J Ophthalmol. 1996;80(9):850–1.

Field, Matthew G, Harbour, William J. National library of medicine. Current Opinion in Ophthalmology. 2014; 25(3):234-9.

Schoenfield, Lynn. Advances in anatomic pathology. National Library of Medicine. 2014;21(2):138-43.

Chen X, Wu Q, Tan L, et al. Methods in molecular biology. Oncogene. 2014;33(39):4724-34.

Hirokawa K, Matsuyama M, Kasai M, Kurashima C. Aging and immunity. Acta Pathol Jpn. 1992;42(8):537-48. doi: 10.1111/j.1440-1827.1992.tb03103.x.

Feng L, Zhu J, Gao T, et al. Uveal melanoma in the peripheral choroid masquerading as chronic uveitis. Optom Vis Sci. 2014;91:e222Ye225.

Duke-Elder S. Uveitis of unknown etiology. System of ophthalmology. Vol. IX. Diseases of the uveal tract. London: Henry Kimpton; 1966. p. 558-602.


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