Comparison of Quality of Life between Patients Undergoing Chronic Hemodialysis with Reusable Dialyzer and Single-Use Dialyzer: A Retrospective Cohort Study

Lucky Aziza Bawazier, Suhardjono Suhardjono


Background: in Indonesia, majority of hemodialysis centers use reusable dialyzer for cost efficiency reason. Currently, there is no available data regarding the quality of life of the end stage-renal disease patientwho use reusable dialyzer measured by a standardized questionnaire, as it was stated that at molecular level, reusable dialyzer could worsen leukocyte activity and could affect patients complaints and symptoms.
Methods: this was a retrospective cohort study which involved 39 subjects. All subjects underwent hemodialysis at Cipto Mangunkusumo Hospital. The study was conducted in March September 2017. All subjects had experienced two kinds of dialyzers, the reusable dialyzers (before 2015) and the single-use dialyzers (after 2015). Of all patients, 19 patients did not know the change of dialyzers. Subjects were interviewed with Kidney Disease Quality of Life-Short Form 36 questionnaire. Results: in kidney disease component dimension, there was a significant mean difference between reusable group (68.74; SD 13.22) and single-use group (74.87; SD 13.54) (Wilcoxon test, p=0.01). The Physical Component Summary dimension, in reusable group was 63.65; SD 27.07 and in single-use group was 69.38; SD 23.07 (Wilcoxon test, p=0.217). The Mental Component Summary dimension, in reusable group was 71.78; SD 21.54 and in single-use group was75.27; SD 22.30 (Wilcoxon test, p=0.127). Bivariate analysis and further analysis showed significant association between income less than 5 million rupiah and low quality of life (p=0.048). Conclusion: the reusable dialyzer membrane lowers the ESRD patients quality of life influenced by another factor such as low income.


Kidney disease quality of life; end-stage renal disease patients; reusable dialyzer; single-use dialyzer


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