1. Home
  2. Vol 53, No 4 (2021)
  3. Nelwan

The Comparison of Point Prevalence Survey (PPS) and Gyssens Flowchart Approach on Antimicrobial Use Surveillance in Indonesian National Referral Hospital

Erni J Nelwan, Helio Guterres, Adeline Intan Pasaribu, Sharifah Shakinah, Ralalicia Limato, Djoko Widodo

Abstract


The antimicrobial resistance (AMR) rate in Indonesia is steadily rising, despite the existing national action plan in 2014. In line with the Global Action Plan on AMR, proper surveillance on antimicrobial usage and resistance are needed. At present, antimicrobial surveillance (AMS) data in Indonesia is heterogeneous, fragmented, and localized. The common method of antimicrobial surveillance (AMS) in referral hospitals is by implementing Gyssens flowchart during Antimicrobial Resistance Control Program Committee clinical rounds. However, the recent method of AMS with Point Prevalence Survey (PPS) offers many advantages include its concise and simple protocol, large data collection, shorter required time, comprehensive data outcomes, real-time data, and standardized parameters. In low-middle income countries such as Indonesia with its restricted resources in AMS, PPS is superior compared to the ‘traditional’ hospital clinical round in generating representative and homogenous outcomes that can be compared to data from other centers worldwide.


Keywords


antimicrobial; Point Prevalence Survey; Gyssens Flowchart; Indonesia

References


Klein EY, Van Boeckel TP, Martinez EM, et al. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proc Natl Acad Sci USA. 2018;115(15):E3463–70.

Parathon H, Kuntaman K, Widiastoety TH, et al. Progress towards antimicrobial resistance containment and control in Indonesia. BMJ. 2017;358:31–5.

Ansari F, Erntell M, Goossens H, Davey P. The european surveillance of antimicrobial consumption (ESAC) point-prevalence survey of antibacterial use in 20 European hospitals in 2006. Clin Infect Dis. 2009;49(10):1496–504.

Hadi U, Duerink DO, Lestari ES, Nagelkerke NJ, Keuter M, Huis D. Audit of antibiotic prescribing in two governmental teaching hospitals in Indonesia. Clin Microbiol Infect. 2008;14(7):698–707. Available from: http://dx.doi.org/10.1111/j.1469-0691.2008.02014.x

Guterres H, Nelwan EJ, Chen LK, Nugroho P. Point prevalence survey of antibiotics use among inpatient in national referral hospital in Indonesia. Int J Infect Dis. 2021;101:2021.

Lestari E, Severin J, Verbrugh H. Antimicrobial resistance among pathogenic bacteria in Southeas Asia. Southeast Asian J Trop Med Public Heal. 43(2):385–422.

World Health Organization. Antimicrobial resistance: global report on surveillance. 2014;35–41.

The Review on Antimicrobial Resistance (Chaired by Jim O’Neill). Tackling Drug-Resistant Infections Globally: Final Report and Recommendations. 2016;(May):1–80.

World Health Organization. JAIPUR: Jaipur declaration on antimicrobial resistance. 2011; Available from: http://www.searo.who.int/%0Aentity/world_health_day/media/2011/whd-11_amr_jaipur_declaration_.pdf

World Health Organization. Global Action Plan on Antimicrobial Resistance. 2015;

World Health Organization (WHO). Central Asian and Eastern European Surveillance of Antimicrobial Resistance. 2018;39. Available from: http://www.euro.who.int/pubrequest%0Ahttp://fossportal/departments/Management/Annual Report/Annual Report English/FOSS AS Annual Report 2017.pdf

European Centre for Disease Prevention and Control. Point prevalence survey of healthcare-associated infections and antimicrobial use in European acute care hospitals 2011–2012. 2019;3.1.2.

European Centre for Disease Prevention and Control. European Antimicrobial Resistance Surveillance Network (EARS-Net) [Internet]. [cited 2021 Mar 7]. Available from: https://www.ecdc.europa.eu/en/about-us/partnerships-and-networks/disease-and-laboratory-networks/ears-net

Pan American Health Organization. Latin American Network for Antimicrobial Resistance Surveillance - ReLAVRA [Internet]. [cited 2021 Mar 7]. Available from: https://www.paho.org/en/topics/antimicrobial-resistance/latin-american-network-antimicrobial-resistance-surveillance

World Health Organization (WHO). Global Antimicrobial Resistance Surveillance System. WHO. 2015;36.

Global PPS. Global point prevalence survey: scientific publications. 2020; Available from: %0Awww.global-pps.com

Gyssens I, van den Broek P, Kullberg B, van der Meer J. Optimizing antimicrobial therapy: a method for antimicrobial drug use evaluation. J Antimicrob Chemother [Internet]. 1992;30:724–7. Available from: https://academic.oup.com/jac/article-abstract/30/5/724/849889?redirectedFrom=fulltext

Magdalena R, Bachtiar A. Antimicrobial Resistance Control Program on the Rational Use of Antibiotics in Eka Hospital Pekanbaru, Indonesia. Proc Int Conf Appl Sci Heal. 2018;(3):374–80.

Karuniawati H, Yulianti T, Aini DK, Nurwienda FI. Impact of antimicrobial stewardship program on the use of antibiotics in pneumonia patients at teaching hospital in surakarta Indonesia. Int J Appl Pharm. 2021;13(special issue 1):20–3.

Yoanitha N, F. Wirakusumah F, Arev Sukarsa MR. Gambaran Rasionalitas Penggunaan Antibiotik berdasarkan Kriteria Gyssens di Bangsal Obstetri dan Ginekologi RSUP Dr. Hasan Sadikin Bandung. Indones J Obstet Gynecol Sci. 2018;1(2):111–6.

Setiawan S, Widyati W, Harijono P. Antibiotic Usage Profile after Antibiotic Stewardship Program Implementation in Intensive Care Unit of dr. Ramelan Naval Hospital Surabaya. Indones J Clin Pharm. 2018;7(1):30–7.

Komite Pengendalian Resistensi Antimikroba RSCM. Kajian resistensi antimikroba di rumah sakit. Jakarta; 2017.

Aldeyab MA, Kearney MP, McElnay JC, Magee FA, Conlon G, Gill D, et al. A point prevalence survey of antibiotic prescriptions: Benchmarking and patterns of use. Br J Clin Pharmacol. 2011;71(2):293–6.

Vandael E, Latour K, Goossens H, Magerman K, Drapier N, Catry B, et al. Point prevalence survey of antimicrobial use and healthcare-associated infections in Belgian acute care hospitals: Results of the Global-PPS and ECDC-PPS 2017. Antimicrob Resist Infect Control. 2020;9(1):1–13.

Porto APM, Goossens H, Versporten A, Costa SF. Global point prevalence survey of antimicrobial consumption in Brazilian hospitals. J Hosp Infect. 2020;104(2):165–71.

Frenette C, Sperlea D, German GJ, Afra K, Boswell J, Chang S, et al. The 2017 global point prevalence survey of antimicrobial consumption and resistance in Canadian hospitals. Antimicrob Resist Infect Control. 2020;9(1):1–9.

Limato R, Nelwan EJ, Mudia M, Brabander J de, Guterres H, Enty E, et al. A multicentre point prevalence survey of patterns and quality of antibiotic prescribing in Indonesian hospitals. 2021;

Kementerian Kesehatan Indonesia. Peraturan Menteri Kesehatan Republik Indonesia nomor 8 tahun 2015 tentang program pengendalian resistensi antimikroba di rumah sakit. 2015; Available from: www.bphn.go.id

Tambunan T. Kebijakan pengendalian resistensi antimikroba. 2019;4–7. Available from: http://parceiro.vitalatman.com.br/cgi-bin/content/view.php?data=kebijakan_pengendalian_resistensi_antimikroba&filetype=pdf&id=3e98db39a5ab9e39f94acd5e9f47c5c2

Rukmini, Siahaan S, Sari ID. Analisis implementasi kebijakan program pengendalian (studi kasus di RSUP Dr . Wahidin Sudirohisudo, Makassar). Bul Penelit Sist Kesehat. 2019;22(2 April 2019):106–16.

Guterres H. Point prevalence survey penggunaan antibiotik pada pasien dewasa rawat inap di RSUPN Cipto Mangunkusumo. Thesis. Universitas Indonesia; 2020.

Gyssens IC. Audits for monitoring the quality of antimicrobial prescriptions. Antibiot Policies Theory Pract. 2005;197–226.

Katarnida SS, Murniati D, Katar Y. Evaluasi penggunaan antibiotik secara kualitatif di RS penyakit infeksi Sulianti Saroso, Jakarta. Sari Pediatr. 2016;15(6):369.

Centers for Disease Control and Prevention. Introduction to public health surveillance [Internet]. 2021 [cited 2021 Mar 15]. Available from: https://www.cdc.gov/training/publichealth101/surveillance.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fpublichealth101%2Fsurveillance.html#:~:text=Public health surveillance is “the,health surveillance systems and methods.

World Health Organization (WHO). WHO methodology for point prevalence survey on antibiotic use in hospitals. 2018; Available from: http://apps.who.int/iris

Goossens H. Protocol: Global Point Prevalence Survey of antimicrobial consumption and resistance. 2020;(May):2–10.

Moro M, Stazi M, Marasca G, Greco D, Zampieri A. National prevalence survey of hospital-acquired infections in Italy, 1983. J Hosp Infect. 1988;8:72–85.

Bernander S, Hambraeus A, Myrback K, Nystrom B, Sundelof BO. Prevalence of hospital-associated infections in five Swedish hospitals in November 1975. Scand J Infect Dis. 1978;10(November 1975):66–70.

Vincent JL, Bihari DJ, Suter PM, et al. The prevalence of nosocomial infection in intensive care units in Europe: results of the European prevalence of infection in intensive care (EPIC) study. JAMA J Am Med Assoc. 1995;274(8):639–44.

Gharbi M, Doerholt K, Vergnano S, et al. Using a simple point-prevalence survey to define appropriate antibiotic prescribing in hospitalised children across the UK. BMJ Open. 2016;6(11):1–8.

Xie D shuang, Xiang L li, Li R, Hu Q, Luo Q qin, Xiong W. A multicenter point-prevalence survey of antibiotic use in 13 Chinese hospitals. J Infect Public Health [Internet]. 2015;8(1):55–61. Available from: http://dx.doi.org/10.1016/j.jiph.2014.07.001

Goossens H, Ferech M, Vander Stichele R, Elseviers M. Outpatient antibiotic use in Europe and association with resistance: A cross-national database study. Lancet. 2005;365(9459):579–87.

Lee C, Walker SAN, Daneman N, et al. Point prevalence survey of antimicrobial utilization in a Canadian tertiary-care teaching hospital. J Epidemiol Glob Health [Internet]. 2015;5(2):143–50. Available from: http://dx.doi.org/10.1016/j.jegh.2014.06.003

Willemsen I, Groenhuijzen A, Bogaers D, Stuurman A, Van Keulen P, Kluytmans J. Appropriateness of antimicrobial therapy measured by repeated prevalence surveys. Antimicrob Agents Chemother. 2007;51(3):864–7.

Yuniar I, Karyanti MR, Tambunan T, Rizkyani NA. Evaluasi penggunaan antibiotik dengan kartu monitoring antibiotik Gyssens. Sari Pediatr. 2016;14(6):384.

Sitompul F, Radji M, Bahtiar A. Evaluasi penggunaan antibiotik dengan metode Gyssens pada pasien stroke rawat inap di RSUD Koja secara retrospektif (Periode KJS dan BPJS). J Kefarmasian Indones. 2016;6(1):30–8.

World Health Organization. Antimicrobial stewardship programmes in health-care facilities in low- and middle-income countries: a WHO practical toolkit [Internet]. Vol. 1, JAC-Antimicrobial Resistance. 2019. Available from: https://academic.oup.com/jac/article-abstract/30/5/724/849889?redirectedFrom=fulltext


Full Text: PDF

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.