Systemic Corticosteroid as an Adjunct for Acute Respiratory Distress Syndrome in Non-Fatal Fresh Water Drowning: An Evidence-based Case Report

Authors

  • Eric Daniel Tenda Division of Respirology and Critical Medicine, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Joshua Henrina Research Assistant, Division of Respirology and Critical Medicine, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Andry Setiadharma Research Assistant, Division of Respirology and Critical Medicine, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Ceva Wicaksono Pitoyo Division of Respirology and Critical Medicine, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Mira Yulianti Division of Respirology and Critical Medicine, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Raden Fidiaji Hiltono Santoso Division of Cardiology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Kuntjoro Harimurti 1. Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia. 2. Center for Clinical Epidemiology and Evidence-Based Medicine, Cipto Mangunkusumo Hospital/ Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
  • Czeresna Heriawan Soejono Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Keywords:

Non-fatal drowning, corticosteroid, acute respiratory distress syndrome, evidence-based case report

Abstract

Background: Acute lung injury or acute respiratory distress syndrome (ARDS) is one of the most common complications of non-fatal drowning. Although respiratory societies’ guidelines endorse the role of systemic corticosteroids in ARDS, the evidence for systemic corticosteroids use in ARDS due to non-fatal drowning is limited. Methods: A search was conducted on Pubmed, OVID, and EuropePMC, assessing the clinical question using inclusion and exclusion criteria. The selected studies were critically appraised, and the results were summarized. Results: A total of six retrospective studies were selected and assessed, all studies showed poor validity and a high risk of bias. Out of six studies, only four informed us of steroid administration's effect on outcomes. In two studies, mortality associated with corticosteroid administration seemed to be higher. On the contrary, one study found no mortality in the corticosteroid group, but 100% mortality was observed in the control group. In another study, steroid therapy seemed to not affect hospital length of stay or mechanical ventilation rates. Conclusion: Corticosteroid administration for non–fatal drowning and its impact on clinical outcomes remain equivocal. Routine administration of corticosteroids is not indicated and should be done on a case-by-case basis.

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Published

2024-07-16

How to Cite

Tenda, E. D., Henrina, J., Setiadharma, A., Pitoyo, C. W., Yulianti, M., Santoso, R. F. H., Harimurti, K., & Soejono, C. H. (2024). Systemic Corticosteroid as an Adjunct for Acute Respiratory Distress Syndrome in Non-Fatal Fresh Water Drowning: An Evidence-based Case Report. Acta Medica Indonesiana, 56(2), 253. Retrieved from https://actamedindones.org/index.php/ijim/article/view/2298

Issue

Vol. 56 No. 2 (2024): Acta Medica Indonesiana

Section

SPECIAL ARTICLE

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